Holidays and Traditions Can you set up Amazon echo with a computer? Can you set up Amazon echo with a computer? The Amazon Echo is not a smart home product that is reliant on a mobile device to operate. Once set up, the Echo is entirely voice-activated, and it's very good at it. And because there's a web app, you can handle everything from your Windows 10 PC. Related Posts:Can Alexa work without electricity?How do I turn on the microphone on my echo show?How to block channels on smart TVs with step-by- step instructions.How do I do a hard reset on my echo dot?