Food and Entertaining How do I use TGIF? How do I use TGIF? TGIF is used to say that you are glad the work week is almost over. TGIF is an abbreviation for 'Thank God it's Friday. ' Related Posts:TGI Fridays have endless apps.What do you learn about God as a promise keeper?What is God's will for our lives?The Beatitudes, Part Four: Hungering and Thirsting