Treatment Recommendations Prevention of acneiform rash caused by EGFR inhibitors includes topical corticosteroids (hydrocortisone 2.5%, alclometasone) and oral antibiotics (minocycline, doxycycline, or antibiotics covering skin flora) twice daily for at least the first 6 weeks.15 May 2013
What causes acneiform folliculitis?
This rash is acneiform folliculitis, which mimics acne but contains no comedones. The eruption may be caused by a host of drugs, including bromides; hormones, including adrenocorticotropic hormone and androgens; corticosteroids; oral contraceptives; iodides; isoniazid; lithium; phenobarbital; and phenytoin.6 Jun 2012
What is a acneiform rash?
The acneiform rash is characterized by erythematous papules and pustules that develop on the face, scalp, and upper trunk within the first month in > 90% of patients. Not only does the rash have a cosmetic impact, but it is frequently associated with pain, infections, and pruritus.15 May 2013
What drugs cause acneiform rash?
There are many causes for acneiform eruptions including exposure to halogenated aromatic hydrocarbons and the use of antibiotics like macrolides and penicillin. Other drugs that can also induce acneiform eruptions include nystatin, isoniazid, corticotropin, naproxen, and hydroxychloroquine.
Treatment varies with the particular disease suspected and consists of a wide range of methods, including excision, laser ablation, topical/oral antibiotics, topical/oral retinoids, and drug withdrawal.29 Jul 2019
What does cetuximab rash look like?
Patients may develop a rash. While this rash may look like acne, it is not, and should not be treated with acne medications. The rash may appear red, swollen, crusty and dry, and feel sore. You may also develop very dry skin, which may crack, be itchy or become flaky or scaly.1 Oct 2021
How long does acneiform rash last?
Acneiform rash is a dose-dependent skin drug reaction, which usually develops in the first 1-2 weeks, peaks at 3-4 weeks on therapy, and its intensity decreases after 2 weeks but can often persist over some months.
How do you treat erlotinib rash?
Erlotinib-related xeroderma should be treated with emollients, with the addition of a topical steroid (at least strong class) for grade 2 severity or higher (Table I). Patients should be switched to a medium-class topical steroid once symptoms improve.
How do you treat immunotherapy rash?
Your doctor may prescribe medicated skin creams for a rash. If the rash is severe or covers a large area of the body, you may need oral corticosteroids, such as prednisone or dexamethasone (available as generic drugs).1 Nov 2021