Alpelisib is the generic name for the trade name drug Piqray®. In some cases, health care professionals may use the trade name Piqray® when referring to the generic drug name alpelisib. Drug type: Alpelisib is an anti-cancer("antineoplastic") chemotherapy drug.
Do you lose your hair with PIQRAY?
The most common side effects of PIQRAY when used with fulvestrant include hyperglycemia, diarrhea, rash, nausea, tiredness and weakness, decreased appetite, mouth sores, vomiting, weight loss, hair loss, and changes in certain blood tests. PIQRAY can also cause more serious side effects.
Can PIQRAY cause diabetes?
High blood sugar levels (hyperglycemia): Hyperglycemia is common with PIQRAY and its complications can be severe. Your health care provider will monitor your blood sugar levels before you start and during treatment with PIQRAY.
How long do patients stay on PIQRAY?
39.3 months for people treated with Piqray and Faslodex. 31.4 months for people treated with Faslodex alone.Oct 16, 2020
How does alpelisib cause hyperglycemia?
In SOLAR-1, a peak in blood glucose was noted at 2 weeks, and discontinuation of alpelisib led to resolution of hyperglycemia. Normally, the p110ɑ subunit of PI3K plays a role in storing glucose as glycogen when insulin levels increase, which then leads to a reduction in blood glucose levels.Jul 23, 2020
What kind of drug is PIQRAY?
Piqray (alpelisib) is a prescription medicine used in men and postmenopausal women with HR-positive, HER2-negative breast cancer that is advanced or has spread to other parts of the body (metastatic). Piqray is used only if your cancer has a specific genetic marker (an abnormal "PIK3CA" gene).Nov 2, 2020
What type of treatment is PIQRAY?
Piqray is a targeted therapy medicine called a PI3K inhibitor that blocks the PI3K pathway. The PI3K pathway helps all cells — both healthy and cancer cells — get the energy they need. When this pathway is overactivated because of a mutation in the PIK3CA gene, it can allow cancer cells to survive and grow.Aug 20, 2021
What is considered a chemotherapy drug?
Chemotherapy is a drug treatment that uses powerful chemicals to kill fast-growing cells in your body. Chemotherapy is most often used to treat cancer, since cancer cells grow and multiply much more quickly than most cells in the body. Many different chemotherapy drugs are available.Mar 5, 2020
What is the best chemotherapy drug?
Doxorubicin (Adriamycin) is one of the most powerful chemotherapy drugs ever invented. It can kill cancer cells at every point in their life cycle, and it's used to treat a wide variety of cancers.