There are three replacement refrigerant options for R12 systems: R134a, R401a, R401b. R134a is regarded, by manufacturers and adherents to the Montreal Protocols alike, as the best replacement refrigerant.Jun 12, 2019
What is a drop-in replacement for R22?
RS-44b (R453a) is the newest R22 drop-in replacement refrigerant in the U.S. market. RS-44b has been sold worldwide for the past 5 years, branded as RS-70 outside the US. It is the closest replacement to R22 that operates with very similar discharge pressure, cooling capacity and flow rate as R22.